Sunlenca (Lenacapavir): A Game-Changer in HIV Treatment
Lenacapavir — also known by its brand name Sunlenca — is being hailed as a breakthrough in HIV care. Imagine only needing an injection twice a year. That’s real freedom from daily pills, especially for those living with drug-resistant HIV.
Of course, like all medications, Sunlenca can come with some side effects. The good news? Most are mild and manageable. Here’s a quick guide to the most common reactions and how to handle them:
1. Injection Site Reactions
What to expect: Redness, swelling, warmth, or tenderness at the injection site (usually the buttock).
Why it happens: The medication is injected deep into the muscle, where it’s slowly released.
How to cope:
- Use a cold compress right after the injection.
- Avoid tight clothing near the area.
- After 24 hours, try gentle stretches or light movement to aid absorption.
2. Nausea
What to expect: A queasy feeling, especially in the first few days after the shot.
Why it happens: Your digestive system may be adjusting to the medication.
How to cope:
- Eat small, frequent meals.
- Avoid spicy, oily foods.
- Sip ginger tea or suck on peppermint.
- Stay hydrated.
- If nausea persists, talk to your doctor about medication options.
3. Fatigue
What to expect: Feeling more tired than usual, even with enough rest.
Why it happens: Your body is adjusting to the drug — immune activity and hormone changes may play a role.
How to cope:
- Prioritize rest, especially in the first week.
- Take light walks to boost circulation.
- Eat iron-rich foods and drink plenty of water.
4. Diarrhoea
What to expect: Loose stools and mild cramping.
Why it happens: The drug may temporarily disturb your gut bacteria.
How to cope:
- Stick to bland, binding foods (bananas, rice, toast).
- Avoid greasy or dairy-heavy meals.
- Take oral rehydration salts (ORS).
- If symptoms last more than a few days, consult your doctor.
5. Headaches
What to expect: Mild tension headaches early in treatment.
Why it happens: This may be due to hormonal shifts or mild immune reactions.
How to cope:
- Rest in a quiet, dark space.
- Drink water regularly throughout the day.
6. Loss of Appeti
What to expect: You may feel less hungry for a few days post-injection.
Why it happens: A temporary response as your body adjusts.
How to cope:
- Eat small, nutrient-rich meals even if you’re not hungry.
- Smoothies, porridge, and soups can help.
- Light activity can naturally boost appetite.
🚨 When to Seek Medical Help
Though rare, serious side effects can occur. Contact your doctor immediately if you experience:
- Signs of an allergic reaction: Severe rash, swelling, or difficulty breathing.
- Liver issues: Yellowing eyes or dark urine.
- Persistent issues: Extreme fatigue, ongoing vomiting, or muscle weakness.
Remember: Your treatment is a journey — and you’re not alone.
Sunlenca offers a powerful new option for living well with HIV
🧡 Read More:
“HIV Doesn’t Define Me” — Bold Kenyans Share Their Stories of Living with HIV/AIDS

