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How to Manage the First 6 Months on Lenacapavir: A Guide to the New Injectable HIV Treatment

Sunlenca (Lenacapavir): A Game-Changer in HIV Treatment

Lenacapavir — also known by its brand name Sunlenca — is being hailed as a breakthrough in HIV care. Imagine only needing an injection twice a year. That’s real freedom from daily pills, especially for those living with drug-resistant HIV.

Of course, like all medications, Sunlenca can come with some side effects. The good news? Most are mild and manageable. Here’s a quick guide to the most common reactions and how to handle them:

1. Injection Site Reactions

What to expect: Redness, swelling, warmth, or tenderness at the injection site (usually the buttock).

Why it happens: The medication is injected deep into the muscle, where it’s slowly released.

How to cope:

  • Use a cold compress right after the injection.
  • Avoid tight clothing near the area.
  • After 24 hours, try gentle stretches or light movement to aid absorption.

2. Nausea

What to expect: A queasy feeling, especially in the first few days after the shot.

Why it happens: Your digestive system may be adjusting to the medication.

How to cope:

  • Eat small, frequent meals.
  • Avoid spicy, oily foods.
  • Sip ginger tea or suck on peppermint.
  • Stay hydrated.
  • If nausea persists, talk to your doctor about medication options.

3. Fatigue

What to expect: Feeling more tired than usual, even with enough rest.

Why it happens: Your body is adjusting to the drug — immune activity and hormone changes may play a role.

How to cope:

  • Prioritize rest, especially in the first week.
  • Take light walks to boost circulation.
  • Eat iron-rich foods and drink plenty of water.

4. Diarrhoea

What to expect: Loose stools and mild cramping.

Why it happens: The drug may temporarily disturb your gut bacteria.

How to cope:

  • Stick to bland, binding foods (bananas, rice, toast).
  • Avoid greasy or dairy-heavy meals.
  • Take oral rehydration salts (ORS).
  • If symptoms last more than a few days, consult your doctor.

5. Headaches

What to expect: Mild tension headaches early in treatment.

Why it happens: This may be due to hormonal shifts or mild immune reactions.

How to cope:

  • Rest in a quiet, dark space.
  • Drink water regularly throughout the day.

6. Loss of Appeti

What to expect: You may feel less hungry for a few days post-injection.

Why it happens: A temporary response as your body adjusts.

How to cope:

  • Eat small, nutrient-rich meals even if you’re not hungry.
  • Smoothies, porridge, and soups can help.
  • Light activity can naturally boost appetite.

🚨 When to Seek Medical Help

Though rare, serious side effects can occur. Contact your doctor immediately if you experience:

  • Signs of an allergic reaction: Severe rash, swelling, or difficulty breathing.
  • Liver issues: Yellowing eyes or dark urine.
  • Persistent issues: Extreme fatigue, ongoing vomiting, or muscle weakness.

Remember: Your treatment is a journey — and you’re not alone.
Sunlenca offers a powerful new option for living well with HIV

🧡 Read More:
“HIV Doesn’t Define Me” — Bold Kenyans Share Their Stories of Living with HIV/AIDS

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